Focus on 2017 Regeneron Scholar Ruiwen (Doris) Fu

By CAROLINE CHEN

Ruiwen (Doris) Fu

Potent Treatment of Renal Fibrosis: A Novel Inhibitor of Hipk2- Smad3 Interaction

After moving to Jericho three years ago, Doris found her voice in science research.
The Regeneron STS Scholar said, “The research community gave me a strength to express myself, a sense of belonging, as well as the confidence to feel like I can ask for help and contribute to a network of brilliant people I admire.”
Not only has research allowed her to gain more knowledge and expand her skillset, it has also allowed for a growth in her personality: “From being afraid of speaking up to presenting to a room of audience confidently, from having difficulty in understanding the articles to writing my own scientific paper; this remarkable feat will continue to enhance my science fervor,” said Doris on how research shaped her into who she is today.

Doris’s research focuses on renal fibrosis, a prevalent detrimental final path of chronic kidney disease for which there is no effective treatment, and addresses the limitations of previous treatments for fibrosis. “From my results, the novel compound BT173 is proposed as a potential medication for renal fibrosis, as well as other related diseases, such as pulmonary fibrosis, atrial fibrosis, cirrhosis, and radiation fibrosis. BT173 can also be suggested as a manipulation tool for future studies of fibrotic diseases.”
Doris has placed 4th at the New York State Science and Engineering Fair (NYSSEF) and earned the Merit Award and Highest Honor/Young Scientist Award at the WAC Lighting Invitational Science Fair and Long Island Science Congress (LISC), respectively, for her previous study in the Plant Science category. Outside of research, Ruiwen is captain of Science Bowl, founder and principal dancer of the Syosset-Jericho Ballet Club, Vice President of the National Latin Honor Society, and a contributing member to the Nassau County All-Star Math Team.

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